Antonis K. Hatzopoulos, PhD

 

Wnt10b Gain-of-Function Improves Cardiac Repair by Arteriole Formation and Attenuation of Fibrosis.

Paik DT, Rai M, Ryzhov S, Sanders LN, Aisagbonhi O, Funke MJ, Feoktistov I, Hatzopoulos AK.

Circ Res. 2015 Oct 9;117(9):804-16. doi: 10.1161/CIRCRESAHA.115.306886. Epub 2015 Sep 3.

PMID:  26338900

 

Endothelial cells contribute to generation of adult ventricular myocytes during cardiac homeostasis.

Fioret BA, Heimfeld JD, Paik DT, Hatzopoulos AK.

Cell Rep. 2014 Jul 10;8(1):229-41. doi: 10.1016/j.celrep.2014.06.004. Epub 2014 Jul 4.

PMID:  25001281

 

Endothelial progenitor cells augment collateralization and hemodynamic rescue in a model of chronic cerebral ischemia.

Hecht N, Schneider UC, Czabanka M, Vinci M, Hatzopoulos AK, Vajkoczy P, Woitzik J.

J Cereb Blood Flow Metab. 2014 Aug;34(8):1297-305. doi: 10.1038/jcbfm.2014.78. Epub 2014 Apr 30.

PMID:  24780900

 

Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.

Tanwar V, Bylund JB, Hu J, Yan J, Walthall JM, Mukherjee A, Heaton WH, Wang WD, Potet F, Rai M, Kupershmidt S, Knapik EW, Hatzopoulos AK.

Stem Cells. 2014 Jul;32(7):1774-88. doi: 10.1002/stem.1703.

PMID:  24648383

 

SDF-1 fused to a fractalkine stalk and a GPI anchor enables functional neovascularization.

Stachel G, Trenkwalder T, Götz F, El Aouni C, Muenchmeier N, Pfosser A, Nussbaum C, Sperandio M, Hatzopoulos AK, Hinkel R, Nelson PJ, Kupatt C.

Stem Cells. 2013 Sep;31(9):1795-805. doi: 10.1002/stem.1439.

PMID:  23744498

 

Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm.

Müller II, Melville DB, Tanwar V, Rybski WM, Mukherjee A, Shoemaker MB, Wang WD, Schoenhard JA, Roden DM, Darbar D, Knapik EW, Hatzopoulos AK.

Dis Model Mech. 2013 Mar;6(2):332-41. doi: 10.1242/dmm.010488. Epub 2012 Dec 7.

PMID:  23223679

 

Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial.

Traverse JH, Henry TD, Pepine CJ, Willerson JT, Zhao DX, Ellis SG, Forder JR, Anderson RD, Hatzopoulos AK, Penn MS, Perin EC, Chambers J, Baran KW, Raveendran G, Lambert C, Lerman A, Simon DI, Vaughan DE, Lai D, Gee AP, Taylor DA, Cogle CR, Thomas JD, Olson RE, Bowman S, Francescon J, Geither C, Handberg E, Kappenman C, Westbrook L, Piller LB, Simpson LM, Baraniuk S, Loghin C, Aguilar D, Richman S, Zierold C, Spoon DB, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD; Cardiovascular Cell Therapy Research Network (CCTRN).

JAMA. 2012 Dec 12;308(22):2380-9. Erratum in: JAMA. 2013 Jan 23;309(4):343. JAMA. 2015 Jul 7;314(1):86.

PMID:  23129008

 

Recent Progress on Chemical Biology of Pluripotent Stem Cell Self-renewal, Reprogramming and Cardiomyogenesis.

Hao J, Sawyer DB, Hatzopoulos AK, Hong CC.

Recent Pat Regen Med. 2011 Sep;1(3):263-274.

PMID:  22787575

 

Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element.

Keilani S, Chandwani S, Dolios G, Bogush A, Beck H, Hatzopoulos AK, Rao GN, Thomas EA, Wang R, Ehrlich ME.

J Neurosci. 2012 May 16;32(20):6808-18. doi: 10.1523/JNEUROSCI.5448-11.2012.

PMID:  22593050

 

Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial.

Perin EC, Willerson JT, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Silva GV, Lai D, Thomas JD, Kronenberg MW, Martin AD, Anderson RD, Traverse JH, Penn MS, Anwaruddin S, Hatzopoulos AK, Gee AP, Taylor DA, Cogle CR, Smith D, Westbrook L, Chen J, Handberg E, Olson RE, Geither C, Bowman S, Francescon J, Baraniuk S, Piller LB, Simpson LM, Loghin C, Aguilar D, Richman S, Zierold C, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD; Cardiovascular Cell Therapy Research Network (CCTRN).

JAMA. 2012 Apr 25;307(16):1717-26. doi: 10.1001/jama.2012.418. Epub 2012 Mar 24. Erratum in: JAMA. 2015 Jul 7;314(1):86.

PMID:  22447880

 

Combinatorial polymer electrospun matrices promote physiologically-relevant cardiomyogenic stem cell differentiation.

Gupta MK, Walthall JM, Venkataraman R, Crowder SW, Jung DK, Yu SS, Feaster TK, Wang X, Giorgio TD, Hong CC, Baudenbacher FJ, Hatzopoulos AK, Sung HJ.

PLoS One. 2011;6(12):e28935. doi: 10.1371/journal.pone.0028935. Epub 2011 Dec 27.

PMID:  22216144

 

Discovering small molecules that promote cardiomyocyte generation by modulating Wnt signaling.

Ni TT, Rellinger EJ, Mukherjee A, Xie S, Stephens L, Thorne CA, Kim K, Hu J, Lee E, Marnett L, Hatzopoulos AK, Zhong TP.

Chem Biol. 2011 Dec 23;18(12):1658-68. doi: 10.1016/j.chembiol.2011.09.015.

PMID:  22195568

 

Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial.

Traverse JH, Henry TD, Ellis SG, Pepine CJ, Willerson JT, Zhao DX, Forder JR, Byrne BJ, Hatzopoulos AK, Penn MS, Perin EC, Baran KW, Chambers J, Lambert C, Raveendran G, Simon DI, Vaughan DE, Simpson LM, Gee AP, Taylor DA, Cogle CR, Thomas JD, Silva GV, Jorgenson BC, Olson RE, Bowman S, Francescon J, Geither C, Handberg E, Smith DX, Baraniuk S, Piller LB, Loghin C, Aguilar D, Richman S, Zierold C, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD; Cardiovascular Cell Therapy ResearchNetwork.

JAMA. 2011 Nov 16;306(19):2110-9. doi: 10.1001/jama.2011.1670. Epub 2011 Nov 14.

PMID:  22084195

 

Programmatic change: lung disease research in the era of induced pluripotency.

Ikonomou L, Hemnes AR, Bilousova G, Hamid R, Loyd JE, Hatzopoulos AK, Kotton DN, Majka SM, Austin ED.

Am J Physiol Lung Cell Mol Physiol. 2011 Dec;301(6):L830-5. doi: 10.1152/ajplung.00255.2011. Epub 2011 Oct 7.

PMID:  21984571

 

Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population.

Wang WD, Melville DB, Montero-Balaguer M, Hatzopoulos AK, Knapik EW.

Dev Biol. 2011 Dec 1;360(1):173-85. doi: 10.1016/j.ydbio.2011.09.019. Epub 2011 Sep 22.

PMID:  21963426

 

Continuous antagonism by Dkk1 counter activates canonical Wnt signaling and promotes cardiomyocyte differentiation of embryonic stem cells.

Rai M, Walthall JM, Hu J, Hatzopoulos AK.

Stem Cells Dev. 2012 Jan;21(1):54-66. doi: 10.1089/scd.2011.0326. Epub 2011 Oct 18.

PMID:  21861760

 

The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis.

Melville DB, Montero-Balaguer M, Levic DS, Bradley K, Smith JR, Hatzopoulos AK, Knapik EW.

Dis Model Mech. 2011 Nov;4(6):763-76. doi: 10.1242/dmm.007625. Epub 2011 Jul 4.

PMID:  21729877

 

Preconditioned endothelial progenitor cells reduce formation of melanoma metastases through SPARC-driven cell-cell interactions and endocytosis.

Defresne F, Bouzin C, Grandjean M, Dieu M, Raes M, Hatzopoulos AK, Kupatt C, Feron O.

Cancer Res. 2011 Jul 15;71(14):4748-57. doi: 10.1158/0008-5472.CAN-10-2449. Epub 2011 May 26.

PMID:  21616936

 

Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.

Wu B, Wang Y, Lui W, Langworthy M, Tompkins KL, Hatzopoulos AK, Baldwin HS, Zhou B.

Circ Res. 2011 Jul 8;109(2):183-92. doi: 10.1161/CIRCRESAHA.111.245035. Epub 2011 May 19.

PMID:  21597012

 

Experimental myocardial infarction triggers canonical Wnt signaling and endothelial-to-mesenchymal transition.

Aisagbonhi O, Rai M, Ryzhov S, Atria N, Feoktistov I, Hatzopoulos AK.

Dis Model Mech. 2011 Jul;4(4):469-83. doi: 10.1242/dmm.006510. Epub 2011 Feb 14.

PMID:  21324930

 

Neuregulin-1β regulation of embryonic endothelial progenitor cell survival.

Safa RN, Peng XY, Pentassuglia L, Lim CC, Lamparter M, Silverstein C, Walker J, Chen B, Geisberg C, Hatzopoulos AK, Sawyer DB.

Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1311-9. doi: 10.1152/ajpheart.01104.2009. Epub 2011 Jan 14.

PMID:  21239627

 

Time is like a clock in my heart: implications for stem cell delivery after myocardial infarction.

Schoenhard JA, Hatzopoulos AK.

Cardiology. 2010;117(2):158-60. doi: 10.1159/000321396. Epub 2010 Oct 30. No abstract available.

PMID:  21042016

 

LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction.

Traverse JH, Henry TD, Vaughan DE, Ellis SG, Pepine CJ, Willerson JT, Zhao DX, Simpson LM, Penn MS, Byrne BJ, Perin EC, Gee AP, Hatzopoulos AK, McKenna DH, Forder JR, Taylor DA, Cogle CR, Baraniuk S, Olson RE, Jorgenson BC, Sayre SL, Vojvodic RW, Gordon DJ, Skarlatos SI, Moyè LA, Simari RD; Cardiovascular Cell Therapy Research Network.

Tex Heart Inst J. 2010;37(4):412-20.

PMID:  20844613

 

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases.

Hammon M, Herrmann M, Bleiziffer O, Pryymachuk G, Andreoli L, Munoz LE, Amann KU, Mondini M, Gariglio M, Airó P, Schellerer VS, Hatzopoulos AK, Horch RE, Kneser U, Stürzl M, Naschberger E.

J Cell Mol Med. 2011 Jul;15(7):1582-92. doi: 10.1111/j.1582-4934.2010.01146.x.

PMID:  20716116

 

Intramyocardial injection of autologous bone marrow mononuclear cells for patients with chronic ischemic heart disease and left ventricular dysfunction (First Mononuclear Cells injected in the US [FOCUS]): Rationale and design.

Willerson JT, Perin EC, Ellis SG, Pepine CJ, Henry TD, Zhao DX, Lai D, Penn MS, Byrne BJ, Silva G, Gee A, Traverse JH, Hatzopoulos AK, Forder JR, Martin D, Kronenberg M, Taylor DA, Cogle CR, Baraniuk S, Westbrook L, Sayre SL, Vojvodic RW, Gordon DJ, Skarlatos SI, Moyé LA, Simari RD; Cardiovascular Cell Therapy Research Network (CCTRN).

Am Heart J. 2010 Aug;160(2):215-23. doi: 10.1016/j.ahj.2010.03.029.

PMID:  20691824

 

Thymosin beta4: a key factor for protective effects of eEPCs in acute and chronic ischemia.

Hinkel R, Bock-Marquette I, Hatzopoulos AK, Kupatt C.

Ann N Y Acad Sci. 2010 Apr;1194:105-11. doi: 10.1111/j.1749-6632.2010.05489.x. Erratum in: Ann N Y Acad Sci. 2010 Sep;1205(1):284. Hazopoulos, Antonis K [corrected to Hatzopoulos, Antonis K].

PMID:  20536456

 

Adriamycin nephropathy: a failure of endothelial progenitor cell-induced repair.

Yasuda K, Park HC, Ratliff B, Addabbo F, Hatzopoulos AK, Chander P, Goligorsky MS.

Am J Pathol. 2010 Apr;176(4):1685-95. doi: 10.2353/ajpath.2010.091071. Epub 2010 Feb 18.

PMID:  20167859

 

Stem cell therapy: pieces of the puzzle.

Schoenhard JA, Hatzopoulos AK.

J Cardiovasc Transl Res. 2010 Feb;3(1):49-60. doi: 10.1007/s12265-009-9148-z. Epub 2009 Nov 19. Review.

PMID:  20119487

 

NF kappaB activation in embryonic endothelial progenitor cells enhances neovascularization via PSGL-1 mediated recruitment: novel role for LL37.

Pfosser A, El-Aouni C, Pfisterer I, Dietz M, Globisch F, Stachel G, Trenkwalder T, Pinkenburg O, Horstkotte J, Hinkel R, Sperandio M, Hatzopoulos AK, Boekstegers P, Bals R, Kupatt C.

Stem Cells. 2010 Feb;28(2):376-85. doi: 10.1002/stem.280.

PMID:  20014279

 

The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.

Schulz H, Kolde R, Adler P, Aksoy I, Anastassiadis K, Bader M, Billon N, Boeuf H, Bourillot PY, Buchholz F, Dani C, Doss MX, Forrester L, Gitton M, Henrique D, Hescheler J, Himmelbauer H, Hübner N, Karantzali E, Kretsovali A, Lubitz S, Pradier L, Rai M, Reimand J, Rolletschek A, Sachinidis A, Savatier P, Stewart F, Storm MP, Trouillas M, Vilo J, Welham MJ, Winkler J, Wobus AM, Hatzopoulos AK; Functional Genomics in Embryonic Stem Cells Consortium.

PLoS One. 2009 Sep 3;4(9):e6804. doi: 10.1371/journal.pone.0006804.

PMID:  19727443

 

Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction.

Traverse JH, Henry TD, Vaughan DE, Ellis SG, Pepine CJ, Willerson JT, Zhao DX, Piller LB, Penn MS, Byrne BJ, Perin EC, Gee AP, Hatzopoulos AK, McKenna DH, Forder JR, Taylor DA, Cogle CR, Olson RE, Jorgenson BC, Sayre SL, Vojvodic RW, Gordon DJ, Skarlatos SI, Moye' LA, Simari RD; Cardiovascular Cell Therapy Research Network (CCTRN).

Am Heart J. 2009 Sep;158(3):356-63. doi: 10.1016/j.ahj.2009.06.009. Epub 2009 Jul 23. Erratum in: Am Heart J. 2009 Dec;158(6):1045. Vaughn, Douglas E [corrected to Vaughan, Douglas E].

PMID:  19699857

 

Stem cell therapy for cardiac repair: benefits and barriers.

Joggerst SJ, Hatzopoulos AK.

Expert Rev Mol Med. 2009 Jul 8;11:e20. doi: 10.1017/S1462399409001124. Review.

PMID:  19586557

 

Cardiac repair and regeneration: the Rubik's cube of cell therapy for heart disease.

Boudoulas KD, Hatzopoulos AK.

Dis Model Mech. 2009 Jul-Aug;2(7-8):344-58. doi: 10.1242/dmm.000240. Review.

PMID:  19553696

 

T17b murine embryonal endothelial progenitor cells can be induced towards both proliferation and differentiation in a fibrin matrix.

Bleiziffer O, Horch RE, Hammon M, Arkudas A, Naschberger E, Rath S, Pryymachuk G, Beier JP, Hatzopoulos AK, Stürzl M, Kneser U.

J Cell Mol Med. 2009 May;13(5):926-35. doi: 10.1111/j.1582-4934.2008.00527.x.

PMID:  19538255

 

Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells.

Hao J, Daleo MA, Murphy CK, Yu PB, Ho JN, Hu J, Peterson RT, Hatzopoulos AK, Hong CC.

PLoS One. 2008 Aug 6;3(8):e2904. doi: 10.1371/journal.pone.0002904.

PMID:  18682835

 

Egr-1 regulates expression of the glial scar component phosphacan in astrocytes after experimental stroke.

Beck H, Semisch M, Culmsee C, Plesnila N, Hatzopoulos AK.

Am J Pathol. 2008 Jul;173(1):77-92. doi: 10.2353/ajpath.2008.070648. Epub 2008 Jun 13.

PMID:  18556777

 

Thymosin beta4 is an essential paracrine factor of embryonic endothelial progenitor cell-mediated cardioprotection.

Hinkel R, El-Aouni C, Olson T, Horstkotte J, Mayer S, Müller S, Willhauck M, Spitzweg C, Gildehaus FJ, Münzing W, Hannappel E, Bock-Marquette I, DiMaio JM, Hatzopoulos AK, Boekstegers P, Kupatt C.

Circulation. 2008 Apr 29;117(17):2232-40. doi: 10.1161/CIRCULATIONAHA.107.758904. Epub 2008 Apr 21.

PMID: 18427126

 

B-Raf-mediated signaling pathway regulates T cell development.

Tsukamoto H, Irie A, Senju S, Hatzopoulos AK, Wojnowski L, Nishimura Y.

Eur J Immunol. 2008 Feb;38(2):518-27. doi: 10.1002/eji.200737430.

PMID:  18228248

 

Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation.

Bidzhekov K, Hautmann M, Semisch M, Weber C, Engelmann B, Hatzopoulos AK.

J Cell Mol Med. 2007 Nov-Dec;11(6):1395-407. doi: 10.1111/j.1582-4934.2007.00123.x.

PMID: 18205709

 

Adenosine receptor-mediated adhesion of endothelial progenitors to cardiac microvascular endothelial cells.

Ryzhov S, Solenkova NV, Goldstein AE, Lamparter M, Fleenor T, Young PP, Greelish JP, Byrne JG, Vaughan DE, Biaggioni I, Hatzopoulos AK, Feoktistov I.

Circ Res. 2008 Feb 15;102(3):356-63. Epub 2007 Nov 21.

PMID:  18032734

 

Biologic properties of endothelial progenitor cells and their potential for cell therapy.

Young PP, Vaughan DE, Hatzopoulos AK.

Prog Cardiovasc Dis. 2007 May-Jun;49(6):421-9. Review.

PMID:  17498522

 

Platelet-induced differentiation of endothelial progenitor cells.

Langer HF, May AE, Vestweber D, De Boer HC, Hatzopoulos AK, Gawaz M.

Semin Thromb Hemost. 2007 Mar;33(2):136-43.

PMID: 17340461

 

Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate.

Diez H, Fischer A, Winkler A, Hu CJ, Hatzopoulos AK, Breier G, Gessler M.

Exp Cell Res. 2007 Jan 1;313(1):1-9. Epub 2006 Sep 19.

PMID:  17045587

 

The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish.

Montero-Balaguer M, Lang MR, Sachdev SW, Knappmeyer C, Stewart RA, De La Guardia A, Hatzopoulos AK, Knapik EW.

Dev Dyn. 2006 Dec;235(12):3199-212.

PMID:  17013879

 

Expression of the protein related to Dan and Cerberus gene--prdc--During eye, pharyngeal arch, somite, and swim bladder development in zebrafish.

Müller II, Knapik EW, Hatzopoulos AK.

Dev Dyn. 2006 Oct;235(10):2881-8.

PMID: 16921498

 

Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A.

Gialitakis M, Kretsovali A, Spilianakis C, Kravariti L, Mages J, Hoffmann R, Hatzopoulos AK, Papamatheakis J.

Nucleic Acids Res. 2006 Feb 1;34(3):765-72. Print 2006.

PMID:  16452299

 

Adherent platelets recruit and induce differentiation of murine embryonic endothelial progenitor cells to mature endothelial cells in vitro.

Langer H, May AE, Daub K, Heinzmann U, Lang P, Schumm M, Vestweber D, Massberg S, Schönberger T, Pfisterer I, Hatzopoulos AK, Gawaz M.

Circ Res. 2006 Feb 3;98(2):e2-10. Epub 2005 Dec 22.

PMID:  16373597

 

Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: role of phosphatidylinositol 3-kinase/AKT kinase.

Kupatt C, Hinkel R, Lamparter M, von Brühl ML, Pohl T, Horstkotte J, Beck H, Müller S, Delker S, Gildehaus FJ, Büning H, Hatzopoulos AK, Boekstegers P.

Circulation. 2005 Aug 30;112(9 Suppl):I117-22.

PMID:  16159802

 

Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia.

Kupatt C, Horstkotte J, Vlastos GA, Pfosser A, Lebherz C, Semisch M, Thalgott M, Büttner K, Browarzyk C, Mages J, Hoffmann R, Deten A, Lamparter M, Müller F, Beck H, Büning H, Boekstegers P, Hatzopoulos AK.

FASEB J. 2005 Sep;19(11):1576-8. Epub 2005 Jul 11.

PMID: 16009705

 

Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.

Jakupoglu C, Przemeck GK, Schneider M, Moreno SG, Mayr N, Hatzopoulos AK, de Angelis MH, Wurst W, Bornkamm GW, Brielmeier M, Conrad M.

Mol Cell Biol. 2005 Mar;25(5):1980-8.

PMID:  15713651

 

Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function.

Conrad M, Jakupoglu C, Moreno SG, Lippl S, Banjac A, Schneider M, Beck H, Hatzopoulos AK, Just U, Sinowatz F, Schmahl W, Chien KR, Wurst W, Bornkamm GW, Brielmeier M.

Mol Cell Biol. 2004 Nov;24(21):9414-23.

PMID:  15485910

 

Embryonic endothelial progenitor cells armed with a suicide gene target hypoxic lung metastases after intravenous delivery.

Wei J, Blum S, Unger M, Jarmy G, Lamparter M, Geishauser A, Vlastos GA, Chan G, Fischer KD, Rattat D, Debatin KM, Hatzopoulos AK, Beltinger C.

Cancer Cell. 2004 May;5(5):477-88.

PMID:  15144955

 

Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis.

Vajkoczy P, Blum S, Lamparter M, Mailhammer R, Erber R, Engelhardt B, Vestweber D, Hatzopoulos AK.

J Exp Med. 2003 Jun 16;197(12):1755-65.

PMID:  12810693

 

Participation of bone marrow-derived cells in long-term repair processes after experimental stroke.

Beck H, Voswinckel R, Wagner S, Ziegelhoeffer T, Heil M, Helisch A, Schaper W, Acker T, Hatzopoulos AK, Plate KH.

J Cereb Blood Flow Metab. 2003 Jun;23(6):709-17.

PMID:  12796719