Blog RSS https://www.vumc.org/global-health/index.php/ en Aurum awarded NIH grant to boost research administration https://www.vumc.org/global-health/index.php/current-research-and-training-programs-latest-news-vigh/aurum-awarded-nih-grant-boost-research <span class="field field--name-title field--type-string field--label-hidden">Aurum awarded NIH grant to boost research administration</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 08/17/2022 - 14:58</span> <a href="/global-health/index.php/blog-post-rss/2828" class="feed-icon" title="Subscribe to Aurum awarded NIH grant to boost research administration"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="field field--name-field-barista-posts-external-url field--type-link field--label-hidden field__item"><a href="https://www.auruminstitute.org/component/content/article/28-blog/aurum-news/670-aurum-awarded-nih-grant-to-boost-research-administration?Itemid=101" target="_blank">https://www.auruminstitute.org/component/content/article/28-blog/aurum-news/670-aurum-awarded-nih-grant-to-boost-research-administration?Itemid=101</a></div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=2111" hreflang="und">Holly Cassell</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2191" hreflang="und">Aurum</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=516" hreflang="und">South Africa</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2164" hreflang="und">Local is Global</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2192" hreflang="und">Research Administration </a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 17 Aug 2022 19:58:19 +0000 ridingkm 2828 at https://www.vumc.org/global-health Vanderbilt-Zambia Cancer Research Training Program (VZCARE) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/vanderbilt-zambia-cancer-research-training-program-vzcare <span class="field field--name-title field--type-string field--label-hidden">Vanderbilt-Zambia Cancer Research Training Program (VZCARE)</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 04/27/2022 - 22:06</span> <a href="/global-health/index.php/blog-post-rss/2813" class="feed-icon" title="Subscribe to Vanderbilt-Zambia Cancer Research Training Program (VZCARE)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>In partnership with the University of Zambia (UNZA) and the Zambia Cancer Diseases Hospital (CDH), the Vanderbilt Institute for Global Health, the Vanderbilt Epidemiology Center and the Vanderbilt-Ingram Cancer Center received $1.3 million for a five-year training grant funded by the National Cancer Institute to support cancer epidemiology research in Zambia.</p> <p>Vanderbilt and UNZA are joining forces to build the Vanderbilt-Zambia Cancer Research Training Program (VZCARE). The VZCARE team is led by <strong>Xiao-Ou Shu, MD, PhD</strong>, professor of Medicine and <strong>Douglas Heimburger, MD</strong>, professor of Medicine from Vanderbilt and <strong>Wilbroad Mutale, PhD, MBChB</strong>, Assistant Dean for Research in the UNZA School of Public Health, lecturer in UNZA’s School of Public Health and Medicine and <strong>Violet Kayamba, PhD, MBChB</strong>, senior lecturer, Department of Internal Medicine, University of Zambia School of Medicine.</p> <p>The overall goal of VZCARE is to develop a cadre of researchers and educators equipped with modern knowledge and expertise to lead cancer epidemiology research and training in Zambia and to encourage US-based researchers to engage in cancer research in low- and middle-income countries.</p> <p>VZCARE builds on the successful 20+ year UNZA-Vanderbilt HIV Research Training Partnership and on the Vanderbilt Epidemiology Center’s global cancer epidemiology expertise, resources, and research training in LMICs.</p> <p>Zambia’s National Cancer Control Strategic plan (2016-2021) lists cancer as one of the four major non-communicable diseases causing disability and premature deaths. By 2040, the burden of cancer in Zambia is expected to increase by 122%. Except for HIV-related malignancies – primarily cervical and Kaposi sarcoma – that have benefited from HIV/AIDS funding, there has been very little investment in Zambian cancer research in general and cancer epidemiology in particular.</p> <p>To develop effective prevention and treatment programs, well-designed studies are urgently needed to identify risk and prognostic factors for cancers, particularly those related to westernization, and for individuals living with HIV. At this time, however, such investigations in Zambia are challenging to implement due to a lack of well-trained investigators experienced in conducting large-scale epidemiologic studies using state-of-the-art methodologies and analysis techniques.</p> <p>Zambia has no cancer epidemiology-specific research training programs to address this workforce gap. There is a pressing need for infrastructure and resource building, leadership development, training of experienced investigators, and development of research methodologies and protocols appropriate to Zambia to fight the country’s growing cancer burden.</p> <p>VZCARE is supported by the NIH-National Cancer Institute D43CA270474.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=2188" hreflang="und">Vanderbilt-Zambia Cancer Research Training Program-VZCARE</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=755" hreflang="und">Douglas Heimburger</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=675" hreflang="und">Xiao-Ou Shu</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2142" hreflang="und">Wilbroad Mutale</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2189" hreflang="und">Violet Kayamba</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=749" hreflang="und">Cancer</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=678" hreflang="und">Zambia</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=253" hreflang="und">Fogarty Training</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=448" hreflang="und">Non-Communicable Diseases</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Thu, 28 Apr 2022 03:06:37 +0000 ridingkm 2813 at https://www.vumc.org/global-health Vanderbilt-Nigeria Biostatistics Training Program (VN-BioStat) https://www.vumc.org/global-health/index.php/VN-BioStat <span class="field field--name-title field--type-string field--label-hidden">Vanderbilt-Nigeria Biostatistics Training Program (VN-BioStat)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Tue, 03/22/2022 - 09:46</span> <a href="/global-health/index.php/blog-post-rss/2805" class="feed-icon" title="Subscribe to Vanderbilt-Nigeria Biostatistics Training Program (VN-BioStat)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Fellowship applications are open for this NIH collaborative research training grant focused on creating a cohort of highly skilled Nigerian biostatisticians with the capacity to lead and supervise high-level biostatistics activities for HIV research studies in West Africa.</p> <p>Focus includes hands-on biostatistics training. Trainees will take biostatistics courses, become members of a team of biostatisticians doing HIV research at Vanderbilt, and will be assigned to HIV research projects using data from Aminu Kano Teaching Hospital (AKTH).</p> <ul><li>Junior investigators with a PhD or “all but dissertation” in statistics or related field, including mathematics and computer science</li> <li>From PhD programs in northern Nigeria, especially Bayero University Kano (BUK) or Ahmadu Bello University</li> <li>12 months of training at Vanderbilt University, Nashville, Tennessee, USA</li> <li>Two semesters of coursework and mentoring at Vanderbilt University</li> <li>Mentorship from faculty at AKTH/BUK and Vanderbilt</li> <li>Provides tuition, school fees, roundtrip airfare to Nashville, living expenses while in Nashville</li> </ul><p>Interested persons should contact: Dr. Nafiu Hussaini, PhD | Bayero University Kano<br /> email: <a href="mailto:nafiu_hussaini@yahoo.com">nafiu_hussaini@yahoo.com</a>  </p> <hr /><p>The Vanderbilt Institute for Global Health (VIGH), the Vanderbilt Department of Biostatistics, and Aminu Kano Teaching Hospital (AKTH), longstanding collaborating institutions in the U.S. and Nigeria, have partnered on a new Training Program from the Fogarty International Center of the National Institutes of Health (NIH). The <strong>Vanderbilt-Nigeria Biostatistics Training (VN-BioStat)</strong> program leverages other successful NIH-funded training and infrastructure programs in Kano, Nigeria (V-BRCH and V-RAMP), building upon a solid foundation of collaborations between Vanderbilt, AKTH, Bayero University Kano (BUK), and Ahmadu Bello University (ABU) in Zaria, Nigeria. The program seeks to create a cohort of highly skilled Nigerian biostatisticians with the capacity to lead and supervise high-level biostatistics activities for HIV research studies in West Africa.</p> <p><meta charset="utf-8" /></p> <p>Drs. Bryan Shepherd, Professor of Biostatistics at Vanderbilt; Nafiu Hussaini, Associate Professor of Mathematical Biology at BUK; and Muktar Aliyu, Professor of Medicine and Health Policy at Vanderbilt and Associate Director for Research with the Vanderbilt Institute for Global Health (VIGH), serve as multiple-principal investigators (MPIs) of VN-BioStat.</p> <p>The program will bring two Nigerian data scientists per year (total of 10 over 5 years) to Vanderbilt to immerse them in hands-on biostatistics training for one-year fellowships. Trainees will take biostatistics courses, become members of a team of biostatisticians doing HIV research at Vanderbilt, and will be assigned to HIV research projects using data from AKTH. The program will also host an annual workshop in Nigeria, team-taught by Vanderbilt and Nigerian investigators, to provide mid-level, hands-on biostatistics training in specific statistical techniques and their applications to HIV research. The workshops will be open to HIV researchers and data scientists from West Africa. </p> <p>This work is supported by the Fogarty International Center of the National Institutes of Health under Award Number 1D43TW012268-01.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=635" hreflang="und">VU Biostatistics</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2184" hreflang="und">Bryan Shepherd</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=420" hreflang="und">Muktar Aliyu</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=441" hreflang="und">Nigeria</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2163" hreflang="und">Infectious Disease </a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Tue, 22 Mar 2022 14:46:51 +0000 ridingkm 2805 at https://www.vumc.org/global-health Aima Ahonkhai receives grant to improve HIV care in Tennessee https://www.vumc.org/global-health/index.php/current-research-and-training-programs-latest-news-vigh/aima-ahonkhai-receives-grant-improve-hiv <span class="field field--name-title field--type-string field--label-hidden">Aima Ahonkhai receives grant to improve HIV care in Tennessee</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Tue, 02/15/2022 - 11:38</span> <a href="/global-health/index.php/blog-post-rss/2798" class="feed-icon" title="Subscribe to Aima Ahonkhai receives grant to improve HIV care in Tennessee"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="field field--name-field-barista-posts-external-url field--type-link field--label-hidden field__item"><a href="https://news.vumc.org/2022/02/24/ahonkhai-advances-in-national-challenge-to-improve-hiv-care-for-black-men-in-tennessee/" target="_blank">https://news.vumc.org/2022/02/24/ahonkhai-advances-in-national-challenge-to-improve-hiv-care-for-black-men-in-tennessee/</a></div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The <a href="https://minorityhealth.hhs.gov/omh/Content.aspx?ID=24556&amp;lvl=2&amp;lvlid=8">Office of Minority Health announced</a> phase one winners of <a href="https://www.minorityhealth.hhs.gov/omh/Content.aspx?ID=22538&amp;lvl=1&amp;lvlid=1&amp;utm_medium=email&amp;utm_source=govdelivery">The HIV Challenge</a>, a national competition seeking innovative approaches to reduce HIV-related stigma and increase prevention and treatment among minority communities. The HIV Challenge provides an opportunity for individuals and organizations to develop novel, innovative approaches for implementation within their local communities. It consists of three phases for concept design, approach development, and refinement with small-scale testing. </p> <p>Assistant Professor of Medicine and core VIGH faculty member <a href="https://www.vumc.org/global-health/index.php/person/aimalohi-aima-ahonkhai-md-mph" target="_blank">Aimalohi "Aima" Ahonkhai, MD, MPH,</a> was one of the 15 winners to receive a prize of $20,000 and will advance to the challenge's second phase. Her proposal focuses on novel strategies utilizing barbers and barbershops to improve HIV care outcomes for Black men with HIV in Middle Tennessee.</p> <blockquote> <p>“Our partnership with Streetworks LLC and barbers in Middle Tennessee has been one of the most motivating research experiences I have had. Our community partners and the barbers themselves have helped me and my team to think outside of the box to meet the needs of young Black men living with HIV in our region, and I am very excited that the HIV challenge will allow me to explore and test these novel ideas” said Ahonkhai.</p> </blockquote> <p>In the U.S., racial and ethnic minority populations have higher HIV diagnoses and lower prevention awareness, treatment initiation, and adherence rates. HIV-related stigma contributes to poor uptake of prevention tools and treatment. Reducing new HIV infections involves community engagement and mobilization strategies to address stigma among at-risk groups. </p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=786" hreflang="und">Aimalohi Ahonkhai</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2171" hreflang="und">Leslie Pierce</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2164" hreflang="und">Local is Global</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=739" hreflang="und">Infectious Diseases</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=306" hreflang="und">HIV</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Tue, 15 Feb 2022 17:38:51 +0000 ridingkm 2798 at https://www.vumc.org/global-health Global Neurosurgery Program https://www.vumc.org/global-health/index.php/current-research-and-training-programs/global-neurosurgery-program <span class="field field--name-title field--type-string field--label-hidden">Global Neurosurgery Program</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Mon, 01/24/2022 - 13:29</span> <a href="/global-health/index.php/blog-post-rss/2792" class="feed-icon" title="Subscribe to Global Neurosurgery Program"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="field field--name-field-barista-posts-external-url field--type-link field--label-hidden field__item"><a href="https://www.vumc.org/neurosurgerydept/global-neurosurgery-research" target="_blank">https://www.vumc.org/neurosurgerydept/global-neurosurgery-research</a></div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=2179" hreflang="und">Neurology/Neurosurgery</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=448" hreflang="und">Non-Communicable Diseases</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=744" hreflang="und">Ethiopia</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=743" hreflang="und">Ghana</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=360" hreflang="und">Kenya</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=441" hreflang="und">Nigeria</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=516" hreflang="und">South Africa</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=529" hreflang="und">Tanzania</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=678" hreflang="und">Zambia</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Mon, 24 Jan 2022 19:29:08 +0000 ridingkm 2792 at https://www.vumc.org/global-health Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II (SPRING) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/primary-prevention-stroke-children-scd-sub-saharan-africa-ii <span class="field field--name-title field--type-string field--label-hidden">Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II (SPRING)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Fri, 11/19/2021 - 14:56</span> <a href="/global-health/blog-post-rss/2786" class="feed-icon" title="Subscribe to Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II (SPRING)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Strokes in sickle cell anemia (SCA), particularly in children living in Africa, are associated with significant morbidity and an increased risk of premature death. In the US, primary stroke prevention in children with SCA involves screening for elevated transcranial Doppler ultrasound (TCD) velocity coupled with regular blood transfusion therapy for those with elevated velocities. However, regular blood transfusion therapy is not feasible in Africa due to inadequate supply of safe blood and the reluctance of parents to accept regular blood transfusion therapy for their children. Promising preliminary data from our feasibility trial in Kano, Nigeria (1R21NS080639-NCE, NCT01801423; October 2012 - August 2014) support the potential use of moderate dose hydroxyurea (HU) therapy of 20 mg/kg/day for primary prevention of stroke in children with SCA.</p> <p>In the feasibility trial, we screened 331 participants; 92% (25 of 27) of participants with elevated TCD measurements elected to enroll and receive HU therapy. About 75% (210 of 280) of the screened participants with non-elevated TCD measurements agreed to be followed for a minimum of three years to assess the background rate of morbidity and mortality. Among those on HU therapy, 80% (20 of 25) of the participants who reached their third month on HU therapy dropped their elevated TCD value to below 200 cm/sec in both middle cerebral arteries. Based on the results from the recently completed Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea trial (NCT01425307), demonstrating that children with an elevated TCD measurement can be switched to HU therapy after one year of blood transfusion, coupled with our preliminary trial results indicating a decrease in TCD velocities in 2/3rds of the participants over 3 months, we propose a three center randomized partial double-blind Phase III clinical trial (1R01NS094041-01; September 2015 - July 2020) to test the following hypothesis: There will be a 66% relative risk reduction of primary strokes in children with SCA, and elevated TCD measurements (n=220), randomly allocated to moderate dose vs. low dose HU therapy (10 vs. 20 mg/kg/day) for 3 years.</p> <p>The aims of the randomized partial double-blind Phase III clinical trial are to: 1) determine the efficacy of moderate vs. low dose HU therapy for primary stroke prevention; 2) determine the efficacy of moderate dose HU therapy for decreasing the incidence of all cause-hospitalization for any cause (pain, acute chest syndrome, infection, or other) when compared to low dose HU therapy; and 3) assess long-term safety of HU therapy (mean 6.5 years) in participants from the feasibility trial with an elevated TCD measurement (n=25), when compared to children with an initial normal TCD (n= 210, followed for at least 3 years). In preparation for this application, the teams from Nigeria have received 1 month of patient-oriented research training at Vanderbilt University School of Medicine. This trial will help us to determine whether moderate dose HU therapy can prevent thousands of strokes in children at high risk in Africa, while simultaneously helping build research capacity among the next cadre of physician scientists in Nigeria.</p> <p><a href="https://clinicaltrials.gov/ct2/show/NCT02560935?term=NCT02560935&amp;draw=2&amp;rank=1">Visit the Clinical Trials website for more information. </a></p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/current-research-and-training-programs?tag=403" hreflang="und">Michael DeBaun</a>, <a href="/global-health/current-research-and-training-programs?tag=2168" hreflang="und">Hematology/Sickle Cell Disease </a>, <a href="/global-health/current-research-and-training-programs?tag=509" hreflang="und">Sickle Cell Disease</a>, <a href="/global-health/current-research-and-training-programs?tag=441" hreflang="und">Nigeria</a>, <a href="/global-health/current-research-and-training-programs?tag=743" hreflang="und">Ghana</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Fri, 19 Nov 2021 20:56:15 +0000 ridingkm 2786 at https://www.vumc.org/global-health Stroke Prevention in Young Adults With Sickle Cell Anemia (SPIYA) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/stroke-prevention-young-adults-sickle-cell-anemia-spiya <span class="field field--name-title field--type-string field--label-hidden">Stroke Prevention in Young Adults With Sickle Cell Anemia (SPIYA)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Fri, 11/19/2021 - 14:50</span> <a href="/global-health/blog-post-rss/2785" class="feed-icon" title="Subscribe to Stroke Prevention in Young Adults With Sickle Cell Anemia (SPIYA)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Sickle cell disease (SCD) is the most common genetic disease, affecting about 25 million people worldwide. Approximately 150,000 Nigerian children are born each year with sickle cell disease (SCD), making it the country with the largest burden of SCD in the world. Recent advancements in care for children with SCA have translated into improved survival of children in both high and low-resource settings. However, more complications of SCD are seen in those who survive to adulthood. Silent cerebral infarcts (SCI) and strokes are among the most devastating complications of SCD, affecting 40% and 10% of children, respectively.</p> <p>The overall goal of this study is to extend the Investigator's successful capacity-building effort in the assessment of neurological morbidity in children with SCD living in northern Nigeria (Kano) to young adults with SCD living in the same region. About 50% of all adults with SCD live in Nigeria. Despite the high prevalence of SCD in Africa, the neurological morbidity is not well characterized, limiting opportunities for primary and secondary stroke prevention strategies. At least 50% of young adults with sickle cell anemia (SCA), the most severe form of the disease, will have SCIs and an estimated 10% will have strokes, based on studies in high-resource settings. In high-resource settings, screening for abnormal transcranial Doppler (TCD) velocities in children with SCA, coupled with regular blood transfusion has resulted in a 92% reduction of relative risk for strokes. Despite this effective strategy, regular blood transfusion therapy does not seem sustainable in sub-Saharan Africa due to shortages and the risk of transfusion transmissible infections. Additionally, there is a lack of evidence-based stroke prevention strategies in young adults with SCA, either in the high-income or in low-resource settings. Based on the foregoing, the Investigators propose to determine the prevalence of neurological injury (overt stroke, transient ischemic attacks, and silent cerebral infarcts) in young adults at the transition age from 16-25 years. The Investigators will also, for the first time, assess conventional risk factors of stroke in the general population to determine whether a different prevention strategy is required to reduce the incidence of neurological injury in this high-risk population.</p> <p><a href="https://clinicaltrials.gov/ct2/show/NCT04808778?term=NCT04808778&amp;draw=2&amp;rank=1">Visit the Clinical Trials website for more information.</a></p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/current-research-and-training-programs?tag=403" hreflang="und">Michael DeBaun</a>, <a href="/global-health/current-research-and-training-programs?tag=509" hreflang="und">Sickle Cell Disease</a>, <a href="/global-health/current-research-and-training-programs?tag=2168" hreflang="und">Hematology/Sickle Cell Disease </a>, <a href="/global-health/current-research-and-training-programs?tag=441" hreflang="und">Nigeria</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Fri, 19 Nov 2021 20:50:15 +0000 ridingkm 2785 at https://www.vumc.org/global-health TN Together: Opioid Abuse and Response https://www.vumc.org/global-health/index.php/current-research-and-training-programs/tn-together-opioid-abuse-and-response <span class="field field--name-title field--type-string field--label-hidden">TN Together: Opioid Abuse and Response</span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/17/2021 - 09:43</span> <a href="/global-health/index.php/blog-post-rss/2783" class="feed-icon" title="Subscribe to TN Together: Opioid Abuse and Response"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Tennessee anti-drug coalitions are working to reduce dependence on harmful and potentially lethal substances such as prescription drugs, alcohol, and tobacco. In partnership with the Hamilton County Coalition, researchers from Vanderbilt University Medical Center (VUMC) collect and analyze program demographics and outcomes. The Nu-Start program provides access to treatment and recovery services for individuals and families overcoming opioid dependency.</p> <p><strong>Carolyn Audet, PhD, MSci</strong>, associate director of the Center for Clinical Quality and Implementation Research and associate professor of Epidemiology and Health Policy leads the VUMC research team.</p> <p>The project is supported by the Tennessee Department of Mental Health and Substance Abuse Services.</p> <p>In partnership with the Hamilton County Coalition, researchers from Vanderbilt University Medical Center collect and analyze  provided this analysis of the Nu-Start program that provides access to treatment and recovery services for individuals and families overcoming opioid dependency.</p> <p>The project is supported by the Tennessee Department of Mental Health and Substance Abuse Services.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=131" hreflang="und">Carolyn Audet</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2172" hreflang="und">Mariah Pettipiece-Phillips</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2164" hreflang="und">Local is Global</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2177" hreflang="und">Substance Abuse</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2169" hreflang="und">Mental Health</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 17 Nov 2021 15:43:32 +0000 ridingkm 2783 at https://www.vumc.org/global-health Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/artificial-intelligencemachine-learning-consortium-advance <span class="field field--name-title field--type-string field--label-hidden"> Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD) </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Tue, 11/16/2021 - 16:53</span> <a href="/global-health/index.php/blog-post-rss/2782" class="feed-icon" title="Subscribe to Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity (AIM-AHEAD) "> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>This summer the National Institutes of Health (NIH) announced a new flagship initiative, the Artificial Intelligence/Machine Learning Consortium to Advance Health Equity and Researcher Diversity, or AIM-AHEAD.</p> <p>The initiative seeks to quell common biases that beset biomedicine and aims specifically to redress two glaring deficits identified by the NIH: a lack of diversity among artificial intelligence researchers and a lack of representation from various segments of society in the data available to support machine learning and the implementation of artificial intelligence in the health domain.</p> <p>The Coordinating Center includes 14 investigators from around the country, among them Vanderbilt University Medical Center’s Toufeeq Ahmed, PhD, MS, assistant professor of Biomedical Informatics, who’s one of nine investigators for the center’s Leadership Core, and Bradley Malin, PhD, Accenture Professor of Biomedical Informatics, Biostatistics and Computer Science, who’s one of three investigators for the center’s Infrastructure Core. </p> <p>Under the leadership of Drs. Toufeeq and Malin, <strong>VIGH member Martin Were, MD, associate professor of Biomedical Informatics and Medicine</strong> will focus on software infrastructure to facilitate artificial intelligence and health disparities research.</p> <p><a href="https://news.vumc.org/2021/10/21/initiative-seeks-to-improve-diversity-of-ai-research/">Full VUMC Reporter Article</a></p> <p><a href="https://aim-ahead.net/home">AIM-AHEAD Website</a></p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=713" hreflang="und">Martin Were</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2165" hreflang="und">mHealth Biomedical Informatics</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Tue, 16 Nov 2021 22:53:51 +0000 ridingkm 2782 at https://www.vumc.org/global-health Applying Research for a Healthy Liberia https://www.vumc.org/global-health/index.php/current-research-and-training-programs/applying-research-healthy-liberia <span class="field field--name-title field--type-string field--label-hidden">Applying Research for a Healthy Liberia</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a>, <a href="/global-health/index.php/current-research-and-training-programs?cat=79" hreflang="und">Education and Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 23:31</span> <a href="/global-health/index.php/blog-post-rss/2726" class="feed-icon" title="Subscribe to Applying Research for a Healthy Liberia"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The University of Liberia College of Health Sciences is the leading educational institution for developing Liberia’s clinicians, researchers, health policymakers and innovators. As one of only two public universities in the country, it is poised to become a globally recognized leader in research utilization, meaningfully connecting academics with policymaking, innovation, and clinical practice. Devastated by civil war, the Ebola epidemic, and now COVID-19, Liberia’s health system has dealt with severe resource constraints, shortages in healthcare workers, and other systemic challenges including gaps in evidence-based medical training and practices. </p> <p>The Vanderbilt Institute of Global Health (VIGH) partnered with Yale University and the University of Liberia College of Health Sciences (ULCHS) to establish a public-private-academic hub for research utilization in the Liberian health sector and an academic network to strengthen Liberia’s education and health sectors.</p> <p>Funding for the Applying Research for a Healthy Liberia project comes from the United States Agency for International Development (USAID), Bringing Research to Impact for Development, Global Engagement, and Utilization (BRIDGE-U) program. It will allow the three institutions to build on a longstanding partnership to create the Center for Teaching, Learning, and Innovation (CTLI) in Liberia.</p> <p>This program builds off the successful implementation of capacity-building activities by the three institutions, including the <a href="https://www.vumc.org/global-health/index.php/current-funding-portfolio-ordered-start-date/residency-integrated-medical-education-and">Partnerships for Enhanced Engagement in Research (PEER Liberia) </a>USAID grant designed to strengthen medical training, build subspecialty medical capacity, and enhance research training in Liberia.</p> <p>The BRIDGE-U program will enhance ULCHS’s role as a national hub for research and interprofessional training by getting a Center for Teaching, Learning, and Innovation fully operational and connecting ULCHS faculty and students directly with policymakers, clinicians, and private-sector innovators to translate research outputs.</p> <p>As an academic hub, CTLI will comprise an experiential learning and assessment lab, a health start-up incubator as well as initiatives to translate and implement existing research findings, and programming to impart research utilization competencies.</p> <p>The BRIDGE-U program is part of <a href="https://www.usaid.gov/hesn/hesn-2-0">USAID’s Higher Education Solutions Network</a>. This network provides a platform for USAID to partner with higher education institutions from around the world to address critical development challenges, build local capacity and cultivate innovation.</p> <p><strong>Program objectives include:</strong></p> <ul><li>Advancing research utilization in health and health sciences education for improved health outcomes and equitable economic growth in Liberia.</li> <li>Building research utilization skills among Liberia’s current and future health sciences students, faculty, clinicians, policymakers, and entrepreneurs.</li> <li>Generating new knowledge about how to translate and utilize research findings more effectively to achieve development goals.</li> </ul><p>Funding for the project comes from award number 7200AA21CA00010.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=2151" hreflang="und">Applying Research for a Healthy Liberia - AR4HL</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=382" hreflang="und">Marie Martin</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=121" hreflang="und">Ann Green</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=544" hreflang="und">Troy Moon</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2148" hreflang="und">Harriett Myers</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=741" hreflang="und">Liberia</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=156" hreflang="und">Capacity Building Research</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Thu, 11 Nov 2021 05:31:33 +0000 ridingkm 2726 at https://www.vumc.org/global-health Optimal Management of HIV Infected Adults at Risk for Kidney Disease in Nigeria https://www.vumc.org/global-health/index.php/current-research-and-training-programs/optimal-management-hiv-infected-adults-risk-kidney-disease <span class="field field--name-title field--type-string field--label-hidden">Optimal Management of HIV Infected Adults at Risk for Kidney Disease in Nigeria </span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" typeof="schema:Person" property="schema:name" datatype="">Visitor</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2142" class="feed-icon" title="Subscribe to Optimal Management of HIV Infected Adults at Risk for Kidney Disease in Nigeria "> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Principal Investigator(s): <br /><a href="https://www.vumc.org/global-health/index.php/person/muktar-aliyu-md-mph-drph">Muktar Aliyu, M.D., M.P.H., Dr.P.H.</a><br /><a href="https://www.vumc.org/global-health/index.php/person/c-william-bill-wester-md-mph">William Wester, M.D., M.P.H.</a></p> <p><strong><a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=9241189&amp;icde=39449508&amp;ddparam=&amp;ddvalue=&amp;ddsub=&amp;cr=1&amp;csb=default&amp;cs=ASC&amp;pball=">Optimal Management of HIV Infected Adults at Risk for Kidney Disease in Nigeria (U01DK112271-01)</a></strong><br /> In this study, we plan to determine the optimal means to manage and thereby reduce the risk of kidney and potentially other end organ complications among genetically at-risk northern Nigerian HIV-infected adults. Based on data from the diabetic literature using medications that block the renin angiotensin aldosterone system (RAAS), we plan to evaluate whether or not RAAS inhibition (using one or two different medications that block RAAS) in HIV-infected adults produces similarly promising results.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=669" hreflang="und">William Wester</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=306" hreflang="und">HIV</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=441" hreflang="und">Nigeria</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=801" hreflang="und">Kidney Disease</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=420" hreflang="und">Muktar Aliyu</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2117" hreflang="und">Donna Ingles</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=448" hreflang="und">Non-Communicable Diseases</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 Visitor 2142 at https://www.vumc.org/global-health Vanderbilt-Nigeria Research Administration and Management Training Program (V-RAMP) https://www.vumc.org/global-health/index.php/v-ramp <span class="field field--name-title field--type-string field--label-hidden">Vanderbilt-Nigeria Research Administration and Management Training Program (V-RAMP)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2701" class="feed-icon" title="Subscribe to Vanderbilt-Nigeria Research Administration and Management Training Program (V-RAMP)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><h2>Upcoming Webinar: <a href="https://us02web.zoom.us/meeting/register/tZ0ufuytpjgjEtV3suUuE_8VIfEtugsBI8Yl">Register HERE</a></h2> <p><img alt="webinar graphic" data-entity-type="" data-entity-uuid="" height="383" src="https://www.vumc.org/global-health/index.php/sites/default/files/V-RAMP%20webinar%208-22.png" width="766" class="align-center" /></p> <hr /><h2>About V-RAMP</h2> <p>Expanding on the decade-long Vanderbilt-AKTH partnership, Aminu Kano Teaching Hospital (AKTH), Bayero University Kano (BUK) in Kano, Nigeria, and the Vanderbilt Institute for Global Health (VIGH) are partnering on a new infrastructure development training program supported by the Fogarty International Center of the National Institutes of Health (NIH). The project will strengthen infrastructure capacity in research administration and research ethics in Nigeria. The Vanderbilt-Nigeria Research Administration and Management Training Program (V-RAMP) will leverage senior research management’s extensive expertise at Vanderbilt.</p> <p>Africa’s most populous country, Nigeria, has seen significant expansion in biomedical research. The increasing volume and complexity of Nigeria’s research activities necessitate measures to improve infrastructure in grants administration (project management, financial accountability, reporting and compliance oversight) and to strengthen ethical frameworks to protect the rights and welfare of research participants. V-RAMP will establish a high-quality research administration environment that is knowledgeable and compliant with the fiscal, management, and ethical standards of sponsored research through fellowships at Vanderbilt, skills-building courses in Nigeria, and administrative process improvements, such as the creation of a Community Advisory Board (CAB).</p> <p>This work is supported by the Fogarty International Center of the National Institutes of Health under Award Number G11TW011819</p> <p> </p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=420" hreflang="und">Muktar Aliyu</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=669" hreflang="und">William Wester</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2111" hreflang="und">Holly Cassell</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2117" hreflang="und">Donna Ingles</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2127" hreflang="und">Aminu Kano Teaching Hospital AKTH and Bayero University Kano</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=441" hreflang="und">Nigeria</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=156" hreflang="und">Capacity Building Research</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 ridingkm 2701 at https://www.vumc.org/global-health Population mobility and retention in HIV care among postpartum women in South Africa https://www.vumc.org/global-health/index.php/current-research-and-training-programs/population-mobility-and-retention-hiv-care-among-postpartum <span class="field field--name-title field--type-string field--label-hidden">Population mobility and retention in HIV care among postpartum women in South Africa</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" typeof="schema:Person" property="schema:name" datatype="">Visitor</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/blog-post-rss/2323" class="feed-icon" title="Subscribe to Population mobility and retention in HIV care among postpartum women in South Africa"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Principal Investigator(s): <br /><a href="https://www.vumc.org/global-health/person/kate-clouse-phd-mph">Kate Clouse, Ph.D., M.P.H.</a></p> <p><a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=8919531&amp;icde=39447271&amp;ddparam=&amp;ddvalue=&amp;ddsub=&amp;cr=4&amp;csb=default&amp;cs=ASC&amp;pball="><strong>Population mobility and retention in HIV care among postpartum women in South Africa (K01MH107256)</strong></a><br /> HIV-positive women in South Africa are at high risk of dropping out of HIV care soon after delivery, endangering the life of the mother and infant. The impact of population mobility around the time of delivery on retention in HIV care is unknown. This mentored K01 award will support training and research to explore the impact of population mobility on retention in postpartum HIV care and gather critical information for the development of future interventions to improve retention in HIV care.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/current-research-and-training-programs?tag=355" hreflang="und">Kate Clouse</a>, <a href="/global-health/current-research-and-training-programs?tag=516" hreflang="und">South Africa</a>, <a href="/global-health/current-research-and-training-programs?tag=315" hreflang="und">HIV/AIDS</a>, <a href="/global-health/current-research-and-training-programs?tag=387" hreflang="und">Maternal and Child Health</a>, <a href="/global-health/current-research-and-training-programs?tag=2163" hreflang="und">Infectious Disease </a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 Visitor 2323 at https://www.vumc.org/global-health UNZA-Vanderbilt Partnership for HIV-NCD Research (UVP-2) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/unza-vanderbilt-partnership-hiv-ncd-research-uvp-2 <span class="field field--name-title field--type-string field--label-hidden">UNZA-Vanderbilt Partnership for HIV-NCD Research (UVP-2)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2722" class="feed-icon" title="Subscribe to UNZA-Vanderbilt Partnership for HIV-NCD Research (UVP-2)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The UNZA-Vanderbilt Training Partnership for HIV-Nutrition-Metabolic Research (UVP-1) and the UNZA-Vanderbilt Partnership for HIV-NCD Research (UVP-2) continue a longstanding training collaboration between the University of Zambia School of Medicine/University Teaching Hospital (UNZA/UTH), Vanderbilt University (VU) and the Vanderbilt Institute for Global Health (VIGH).</p> <p>As access to antiretroviral therapy for HIV has expanded in sub-Saharan Africa, millions of persons with HIV are surviving for decades on treatment, but they are developing chronic non-communicable disease (NCD) complications that require new science and new directions in prevention, detection, and treatment. Recognizing that investigation and control of NCDs can be most effectively undertaken by highly trained local investigators, UNZA identified the need for doctoral-level research leaders in nutritionally- and metabolically related complications and comorbidities of HIV. UVP-1 supported this effort through training and education initiatives while expanding UNZA/UTH’s research training and investigative capacities.</p> <p><strong>Key successes of UVP-1 included:</strong></p> <ul><li>Long-term research training for advanced UNZA trainees and junior faculty members, leading to 11 “sandwich” Ph.D. degrees awarded by UNZA and undergirded by Vanderbilt didactic courses, research mentorship, and institutional resources. Between 2015 and 2020, trainees produced 72 manuscripts, 100 presentations at global conferences, and 14 funded grants.</li> <li>Enhancement of the UNZA Ph.D. program through conducting in-country consultations and skill-building short courses, culminating in a redesign of the Ph.D. core curriculum led by UNZA faculty</li> <li>Establishment of the<strong> <a href="https://www.vumc.org/global-health/index.php/latest-news-vigh/why-mentorship-matters-low-and-middle-income-countries">UNZA Mentoring Programme</a></strong>, a week-long faculty development training program to strengthen Ph.D. mentoring standards and assess measurable milestones</li> <li>Annual scientific research conferences held at UNZA, with topics focused on cardiovascular disease, cancer, NCDs, nutrition, and research methods</li> <li>Advanced career opportunities for research-focused UNZA faculty members through 4-month VU-based postdoctoral sabbaticals, expanded research collaborations, and grantsmanship training</li> </ul><p>UVP-1 was led by Douglas C. Heimburger, MD, MS, professor of medicine in the Vanderbilt Institute for Global Health, and Selestine H. Nzala, MBChB, MPH, Head of the Department of Medical Education Development at UNZA School of Medicine. UVP-1 has now transitioned to UVP-2 and is led by Wilbroad Mutale, Ph.D., MBChB, associate professor in the University of Zambia School of Public Health and adjunct associate professor in the Vanderbilt Department of Medicine.</p> <p>UVP-2 will continue the advancement of UNZA’s institutional research capacity and academic leadership. Demonstrating UNZA’s leadership and VIGH’s commitment to strengthening capacities, UNZA is the prime institution for the UVP-2 grant.</p> <p>This grant will extend the “sandwich” model of Ph.D. training and use a similar model to develop a postdoctoral training fellowship program to create a pipeline of independent scientists at UNZA. Through this grant, new research training mechanisms and support structures will be introduced at UNZA to ensure local sustainability</p> <p>Collaborations with other regional universities will be leveraged to provide research training opportunities and increased networks. Bioinformatics training opportunities for selected trainees will be provided through a collaboration with the University of the Witwatersrand in South Africa. Additional collaborations will be built through the Consortium for Advanced Research Training in Africa (CARTA), an Africa-based, Africa-led initiative that has 20-year funding to strengthen the capacity of African universities to produce well-trained and skilled researchers and scholars in Africa.</p> <p>Key components and innovations of UVP-2 include:</p> <ul><li>Train 5 UNZA Ph.D. students and 4 UNZA postdoctoral scientists in advanced basic, clinical/translational, epidemiologic, and implementation sciences to address the complications and comorbidities most relevant to lifelong HIV management in sub-Saharan Africa</li> <li>Support UNZA’s new postdoctoral fellowship mechanism by replicating key Vanderbilt career development resources at UNZA, principally those associated with successful grant applications, and three-month sabbaticals for 4 UNZA Visiting Faculty Scholars at Vanderbilt, focused on developing collaborations and submitting grant applications</li> <li>Develop an UNZA Biostatistics Support Core with a goal of providing structured biostatistics advising and collaboration by UNZA biostatisticians to UNZA investigators, students, and postdoctoral fellows</li> <li>Strengthen UNZA’s capacity to train researchers, attract research funding, and generate high-impact research outputs across a broad range of HIV-NCD investigations</li> </ul><p>Both cycles of UVP have been supported by grant D43TW009744 from the Fogarty International Center of the US National Institutes of Health.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=2142" hreflang="und">Wilbroad Mutale</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=755" hreflang="und">Douglas Heimburger</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=555" hreflang="und">University of Zambia School of Medicine/University Teaching Hospital (UNZA/UTH)</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=448" hreflang="und">Non-Communicable Diseases</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=315" hreflang="und">HIV/AIDS</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=678" hreflang="und">Zambia</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2111" hreflang="und">Holly Cassell</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=711" hreflang="und">Elizabeth Rose</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2163" hreflang="und">Infectious Disease </a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 ridingkm 2722 at https://www.vumc.org/global-health Higher Education Partnership for Innovation and Sustainable Biomedical Informatics Capacity in Kenya (PISBIC Kenya) https://www.vumc.org/global-health/index.php/current-program/PISBIC <span class="field field--name-title field--type-string field--label-hidden">Higher Education Partnership for Innovation and Sustainable Biomedical Informatics Capacity in Kenya (PISBIC Kenya)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/leadee1-0" typeof="schema:Person" property="schema:name" datatype="">leadee1</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2351" class="feed-icon" title="Subscribe to Higher Education Partnership for Innovation and Sustainable Biomedical Informatics Capacity in Kenya (PISBIC Kenya)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p><strong>PI: <a href="https://www.vumc.org/global-health/index.php/person/martin-c-were-md-ms">Martin C. Were, M.D., M.S. </a></strong></p> <p>VIGH core faculty member <strong><a href="https://www.vumc.org/global-health/index.php/person/martin-c-were-md-ms" rel="noreferrer" target="_blank">Martin Were</a>, M.D., M.S.</strong>, associate professor of Biomedical Informatics and Medicine, was recently awarded a cooperative agreement from the United States Agency for International Development (USAID) to establish the Higher Education Partnership for Innovation and Sustainable Biomedical Informatics Capacity in Kenya (PISBIC Kenya).  </p> <p>PISBIC Kenya focuses on building workforce capacity; building evidence about the impact, costs, and benefits of health informatics systems; and producing locally responsive digital health solutions.</p> <p>The program is a partnership between Moi University's Institute of Biomedical Informatics and Aga Khan University in Kenya and Vanderbilt University Medical Center and Purdue University in the United States. Dr. Were and his team will pursue the project goals to further the use of digital health technologies in order to improve health care quality, patient and population health outcomes, and data-driven decision-making to improve healthcare delivery systems.</p> <p>This program is one of four projects under the <strong><a href="https://www.vumc.org/global-health/index.php/sites/default/files/documents/ALP%20one%20pager%202.25.19.pdf">Accelerating Local Potential Program</a></strong> umbrella to help propel "higher education institutions in low- and middle-income countries to become global leaders in scientific education and research, and to increase their presence as a source of knowledge and innovation for local government officials, policy makers, and other development actors."</p> <p>PISBIC Kenya is supported by the U.S. Agency for International Development (USAID), the world's premier international development agency and a catalytic actor driving development results. USAID's work advances U.S. national security and economic prosperity, demonstrates American generosity, and promotes a path to recipient self-reliance and resilience. For more info, visit <a href="https://www.usaid.gov/">www.usaid.gov</a>.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=713" hreflang="und">Martin Were</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=360" hreflang="und">Kenya</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2117" hreflang="und">Donna Ingles</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2165" hreflang="und">mHealth Biomedical Informatics</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 leadee1 2351 at https://www.vumc.org/global-health Vanderbilt Institute for Research Development and Ethics (VIRDE) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/vanderbilt-institute-research-development-and-ethics-virde <span class="field field--name-title field--type-string field--label-hidden">Vanderbilt Institute for Research Development and Ethics (VIRDE)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2723" class="feed-icon" title="Subscribe to Vanderbilt Institute for Research Development and Ethics (VIRDE)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>VIRDE is an annual intensive research training program designed to facilitate trainee research productivity in low- and middle-income countries (LMICs). This month-long program is intended to bolster and further develop the skill sets necessary for conducting responsible human subjects’ research and developing a grant proposal for submission. Attendees participate in a series of grant writing, research ethics/scientific integrity, and career development seminars and workshops. Additionally, each attendee is paired with a Vanderbilt faculty mentor to promote their scientific research development.</p> <p>Elite health professionals, including Fogarty training grant alumni, engaged in research are eligible to apply to VIRDE. The program is open only to LMIC biomedical and public health researchers and is supported by VIGH’s training and research grants. This program is directed by VIGH and occurs at Vanderbilt.</p> <p>In over a decade, VIRDE has trained nearly 60 scholars from 10 countries, 83% of whom have submitted grants after participating in VIRDE. Among those who submitted grants, 85% have received funding and 91% are principal investigators (including co-PI and multi-PI) on these grants. Grant funding comes from diverse sources including US and European government funds, national organizations, foundations, and pharmaceutical companies.</p> <p><strong>Program Evaluation Publication</strong></p> <p>Cassell HM, Rose ES, Moon TD, Bello-Manga H, Aliyu MH, Mutale W. <a href="https://pubmed.ncbi.nlm.nih.gov/35164739/"><strong>Strengthening research capacity through an intensive training program for biomedical investigators from low- and middle-income countries: the Vanderbilt Institute for Research Development and Ethics (VIRDE).</strong></a> BMC Med Educ. 2022 Feb 14;22(1):97. doi: 10.1186/s12909-022-03162-8. PMID: 35164739; PMCID: PMC8842898.</p> <p><strong>Program Evaluation Presentation</strong></p> <p><a href="https://drive.google.com/file/d/1h-E61CPYJ2OjtmcezLQkSdH61AcTSzEJ/view?usp=sharing">View Presentation Slides</a></p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=2111" hreflang="und">Holly Cassell</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=579" hreflang="und">Vanderbilt Institute for Research Development and Ethics (VIRDE)</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=403" hreflang="und">Michael DeBaun</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=420" hreflang="und">Muktar Aliyu</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=711" hreflang="und">Elizabeth Rose</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 ridingkm 2723 at https://www.vumc.org/global-health Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contacts https://www.vumc.org/global-health/index.php/current-research-and-training-programs/immunogenetic-predictors-active-and-incipient-tb-hiv <span class="field field--name-title field--type-string field--label-hidden">Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contacts</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2404" class="feed-icon" title="Subscribe to Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contacts"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p><strong>Principal Investigators: </strong></p> <p><a href="https://www.vumc.org/global-health/index.php/person/timothy-r-sterling-md">Timothy Sterling, MD</a><br /> Bruno Andrade<br /> Thomas Hawn</p> <p>Critical to preventing tuberculosis (TB) is a better understanding of the protective and predisposing factors for progression from M. tuberculosis infection to TB disease. Our group has reported a peripheral blood correlate of risk (COR) transcriptional signature that identified persons with incipient (asymptomatic) TB who progressed to active (symptomatic)TB within 12 months, and also human genetic polymorphisms in a DNA sensor gene region (PYHIN1-IFI16-AIM2) associated with TB risk. We seek to evaluate the immunogenetic and epidemiologic risk factors for active and incipient TB in a Brazilian cohort of HIV-negative and HIV-positive close TB contacts, to identify host pathways associated with protection against TB (for future vaccines), and to identify persons who would benefit from TB preventive therapy.</p> <p>Drs. Timothy Sterling, Bruno Andrade (Instituto Brasileiro para Investigação da Tuberculose (IBIT), Salvador, Brazil), and Thomas Hawn (University of Washington) received a 5 year R01 grant from the National Institutes of Health entitled, “Immunogenetic predictors of active and incipient TB in HIV-negative and -positive close TB contacts” (R01AI147765). This was in response to PAR-16-254, "Mechanisms of Mycobacterial-Induced Immunity in HIV-Infected and Uninfected Individuals to Inform Innovative Tuberculosis Vaccine Design (R01)." Total funding awarded for the 5-year project is $3.6 million, with subcontracts to the Fundação para o Desenvolvimento Científico e Tecnológico em Saúde (FIOTEC; Brazil), the University of Washington, and the University of Cape Town (South Africa). Collaborators include Spyros Kalams, Simon Mallal, Mark Pilkinton, and Peter Rebeiro at Vanderbilt; Valeria Rolla, Afranio Kritski, Marcelo Cordeiro Santos, Solange Cavalcante, Cristina Lourenco, and Ricardo Khouri in Brazil; Javeed Shah at the University of Washington; and Mark Hatherill, Thomas Scriba, and Stanley Kimbung at the University of Cape Town.</p> <p>This grant project seeks to understand the protective and predisposing factors for progression from M. tuberculosis infection to TB disease. The group has previously reported a peripheral blood correlate of risk (COR) transcriptional signature that identifies persons with incipient (asymptomatic) TB who subsequently progress to active (symptomatic) TB within 12 months, and also human genetic polymorphisms in a DNA sensor gene region (PYHIN1-IFI16-AIM2) associated with TB risk. In this project, the group will evaluate innate immune responses in macrophages and their correlates with human genetic polymorphisms, acquired immunity to M. tuberculosis, and epidemiologic factors associated with the risk of incipient and active TB. These studies will be performed in the Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil cohort, which includes culture-confirmed TB cases and their close contacts in racially and ethnically diverse Brazil. This work may identify host pathways associated with protection against TB (for future host-directed therapies and vaccines), and to identify persons infected with M. tuberculosis who would benefit most from TB preventive therapy.</p> <p><a href="https://projectreporter.nih.gov/project_info_description.cfm?aid=9848749&amp;icde=45469321">MORE from the NIH Reporter website</a></p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=537" hreflang="und">Timothy Sterling</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=782" hreflang="und">Tuberculosis</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=306" hreflang="und">HIV</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2163" hreflang="und">Infectious Disease </a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=732" hreflang="und">Brazil</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 ridingkm 2404 at https://www.vumc.org/global-health Improving Perioperative Anesthesia Care and Training in Africa (ImPACT Africa) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/improving-perioperative-anesthesia-care-and-training-africa <span class="field field--name-title field--type-string field--label-hidden">Improving Perioperative Anesthesia Care and Training in Africa (ImPACT Africa) </span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2725" class="feed-icon" title="Subscribe to Improving Perioperative Anesthesia Care and Training in Africa (ImPACT Africa) "> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p style="margin-bottom:11px">The Improving Perioperative Anesthesia Care and Training in Africa (ImPACT Africa) program addresses the critical need for safe surgery by training local anesthesia providers and building educational capacity of local institutions. Vanderbilt Institute for Global Health (VIGH) faculty members, Marie Martin and Elizabeth Rose, along with other VIGH staff and student collaborators, have partnered with ImPACT Africa leaders to provide education consulting and develop new courses.</p> <p>In 2017, our team developed a digital course in Research Methodology. This course was initially designed to be used in a flipped classroom model for trainees in ImPACT Africa’s Kenya Registered Nurse Anesthetist program. The course has since been used by other training groups, including surgery residents and anesthesiologists. The course is structured around seven modules on research development and dissemination and course materials include 35 engaging, didactic videos, supplemental articles, and datasets for practice analyzing data. The digital nature of the course allows for it to be utilized in a classroom structure or as independent learning modules to refresh knowledge on research methodology.</p> <p>In 2020, our team was invited to design a faculty development program for early career anesthesiologists in Ethiopia. The Training of the Trainers (ToT) Course for Physician Anesthesia Educators was developed to enhance knowledge and skills in teaching, leading, and mentoring among faculty trainees. The course includes eleven modules on theories, methods, and best practices. These modules were taught online synchronously via Zoom. The course was developed in a train-the-trainer model so that trainees could become future trainers. After the conclusion of the course in Ethiopia, trainees facilitated the course in Tanzania. Plans are underway for future courses that will be taught by these groups of trainees.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=2153" hreflang="und">Improving Perioperative Anesthesia Care and Training in Africa - ImPACT Africa </a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=382" hreflang="und">Marie Martin</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=711" hreflang="und">Elizabeth Rose</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2154" hreflang="und">Faculty Development</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=448" hreflang="und">Non-Communicable Diseases</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=360" hreflang="und">Kenya</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=744" hreflang="und">Ethiopia</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=529" hreflang="und">Tanzania</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 ridingkm 2725 at https://www.vumc.org/global-health The Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/partnership-research-emerging-viral-infections-sierra-leone <span class="field field--name-title field--type-string field--label-hidden">The Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL) </span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2410" class="feed-icon" title="Subscribe to The Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL) "> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p style="margin-bottom:11px">The West African Ebola outbreak of 2014-2015 exposed the fragility of Sierra Leone’s health system and highlighted the need for further investments to ensure its future capability of responding to a disease outbreak of this magnitude. The goal of our project is to design and conduct health services research and that can generate the evidence needed for improving the delivery of quality health services for patients with endemic viral hemorrhagic fevers (VHF) such as Lassa fever, as well as emerging infections such as SARS-CoV-2.  In addition, we aim to strengthen in-country capacity for the conduct of clinical trials, with a special emphasis on vaccine studies. In 2018, Principal Investigators Drs. Troy Moon (VUMC), John Schieffelin (Tulane University), and Donald Grant (University of Sierra Leone and Kenema Government Hospital) completed a one-year planning grant funded by the Fogarty International Center at NIH that allowed our consortium to evaluate the existing research capacity of our in-country partner organizations, while refining our strategies for best approaches to address gaps in that capacity. This experience, along with our team’s extensive knowledge and history of conducting research in Sierra Leone, allowed us to develop the Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL), a five-year project to substantially advance implementation science research capacity at Sierra Leone’s principal medical school, the College of Medicine and Allied Health Sciences (COMAHS) of the University of Sierra Leone (USL); as well as clinical trial capacity at the Kenema Government Hospital (KGH).</p> <p><strong>Our Specific Aims are to:</strong></p> <p>1) Enhance research capacity at KGH and COMAHS for the conduct of scientifically valid and ethically acceptable clinical trials, with a focus on emerging infections.</p> <p>2) Strengthen and expand the KGH and COMAHS research pool with a focus on Implementation Science research for the clinical management of patients with VHF and other emerging infections.</p> <p>3) Nurture innovative mentored research by PREVSL trainees/alumni to address the clinical management of VHF.</p> <p><strong>Training plan:</strong></p> <p>Our comprehensive training program consists of a combination of:</p> <ul><li>Long-term Master’s training in clinical investigation (MSCI) with a focus on vaccine clinical trial capacity (Vaccine Fellowship at the Vanderbilt Vaccine Research Program VVRP)</li> <li>Short- to medium-term clinical trial management training that reinforces south-south collaborations and builds regional networks</li> <li>Short and long-term capacity building in health services implementation science research through in-country short courses and master’s training in Public Health</li> <li>Sustainable capacity building at KGH and COMAHS for the management and administration of future research grant opportunities</li> </ul><p>Our first trainee from Sierra Leone, Dr. Robert Samuels, completed the two-year MSCI degree which consisted of a one-year Vaccine Fellowship at the VVRP. His Master’s thesis consisted of an evaluation of the clinical presentation and management of children with Lassa Fever in Sierra Leone, which was published in <a>AJTMH</a>.  During his VVRP fellowship, Dr. Samuels served as a research assistant on the Moderna phase III mRNA clinical trial for COVID-19.  This experience led to two publications, one in JAMA and the other in the NEJM.  In addition, Dr. Samuels designed and began implementation of a study, at KGH in Sierra Leone, to evaluate the prevalence of respiratory syncytial virus and influenza in hospitalized children less than two-years of age.</p> <p>Our second trainee, Dr Foday Morovia has completed his first year of classes in the MSCI program and is currently beginning his fellowship with the VVRP.  His research interests include improving the clinical management of patients with VHF like Lassa and Ebola as well as in exploring ways to reduce antimicrobial resistance in Sierra Leone’s health care system.  Dr. Morovia is expected to graduate in 2022.</p> <p>The Fogarty International Center supports this project under agreement <a href="https://reporter.nih.gov/search/8Ibn6XrAVEWQPRxmm78oiA/project-details/10149441">5U2RTW011248</a>.</p> <div> <div> <div id="_com_1" language="JavaScript" onmouseout="msoCommentHide('_com_1')" onmouseover="msoCommentShow('_anchor_1','_com_1')"> <p> </p> </div> </div> </div> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=544" hreflang="und">Troy Moon</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=742" hreflang="und">Sierra Leone</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=156" hreflang="und">Capacity Building Research</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=792" hreflang="und">Viral Hemorrhagic Fevers</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=221" hreflang="und">Ebola</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=121" hreflang="und">Ann Green</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2148" hreflang="und">Harriett Myers</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2163" hreflang="und">Infectious Disease </a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 ridingkm 2410 at https://www.vumc.org/global-health Collaborative Research Ethics Education-Mozambique (Formaçao Colaborativa em Etica na Pesquisa, FoCEP) https://www.vumc.org/global-health/index.php/current-research-and-training-programs/collaborative-research-ethics-education-mozambique-formacao <span class="field field--name-title field--type-string field--label-hidden">Collaborative Research Ethics Education-Mozambique (Formaçao Colaborativa em Etica na Pesquisa, FoCEP)</span> <div class="field field--name-field-barista-posts-category field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/global-health/index.php/current-research-and-training-programs?cat=2170" hreflang="und">Research-Training</a></div> </div> <span class="field field--name-uid field--type-entity-reference field--label-hidden"><span lang="" about="/global-health/index.php/users/ridingkm-0" typeof="schema:Person" property="schema:name" datatype="">ridingkm</span></span> <span class="field field--name-created field--type-created field--label-hidden">Wed, 11/10/2021 - 11:31</span> <a href="/global-health/index.php/blog-post-rss/2411" class="feed-icon" title="Subscribe to Collaborative Research Ethics Education-Mozambique (Formaçao Colaborativa em Etica na Pesquisa, FoCEP)"> RSS: <i class="fa fa-rss-square"></i> </a> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p style="margin-bottom:8px">The growth in research activity projected for the next decade by the Mozambican government and international agencies highlights the continued need for capacity building in research ethics well into the future. With the groundwork laid for systems of basic, translational, clinical and public health research, capacity development in research ethics has been essential to address critical research questions in an ethically consistent way. The four most evident areas in which attention is still needed are:</p> <ol><li>Ethics education, review and oversight of graduate and professional student researchers and their thesis research projects</li> <li>The growth of research using biological specimens and clinical and epidemiologic data, including the development of biobanks and a national data warehouse</li> <li>Research on the prevention and treatment of infectious and non-communicable diseases</li> <li>International collaborative research that requires dual review and agreement on the authority of the potentially different regulatory requirements of partner countries.</li> </ol><p>To address the above needs, we have formed a consortium of partners consisting of University Eduardo Mondlane in Maputo, Mozambique; Vanderbilt University Medical Center; and University of Texas Southwestern called the Collaborative Research Ethics Education program  (Formação Colaborativa em Etica na Pesquisa, FoCEP).</p> <p>Since its launch in 2014, the FoCEP program has focused on supporting the education and research of Master’s students in Public Health at UEM with a special emphasis on research ethics; in modernizing and strengthening the instruction of research ethics in UEM’s health sciences education, and in strengthening the functioning and capacity of Mozambique’s newly created network of Institutional Research Ethics Committees (REC).</p> <p>Renewed for a second five-year period, our Specific Aims currently are to:</p> <ul><li>Expand of the cadre of Mozambican leaders in biomedical research with in-depth knowledge and practical skills in both research design and the ethical conduct of clinical and epidemiologic research through a tailored Master of Public Health (MPH) program and masters-level curriculum enhancements at University Eduardo Mondlane’s Faculty of Medicine (Mozambique’s primary medical school).</li> <li>Enhancement of the knowledge and practical skills of Mozambican REC members and research educators in research ethics, the responsible conduct of research, and research integrity.</li> <li>Further creation, evaluation, and distribution of curricular materials on research ethics and the responsible conduct of research tailored to Portuguese-speaking Africa.</li> </ul><p>Currently, three FoCEP scholars are working towards their MPH degree at UEM with a special emphasis on biomedical ethics. Their training includes participation in a monthly virtual seminar series on topics of relevance in biomedical ethics and focusing their master’s thesis to topics that include an ethics-based research question. These scholars are also working with MPI Esperança Sevene and the FoCEP team on a research protocol assessing the ethical implications on research, ethics committees, and healthcare access in Mozambique during the COVID-19 pandemic.</p> <p>The Fogarty International Center (FIC) supports this project under agreement 5R25TW009722.</p> </div> <div> <strong>Tags</strong> <div> <div><a href="/global-health/index.php/current-research-and-training-programs?tag=544" hreflang="und">Troy Moon</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=414" hreflang="und">Mozambique</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=231" hreflang="und">Ethics</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=553" hreflang="und">University Eduardo Mondlane (UEM)</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=121" hreflang="und">Ann Green</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2148" hreflang="und">Harriett Myers</a>, <a href="/global-health/index.php/current-research-and-training-programs?tag=2106" hreflang="und">Elizabeth Heitman</a></div> </div> </div> <div class="field field--name-field-lockdown-auth field--type-string field--label-above"> <div class="field__label">Lockdown Auth</div> <div class="field__item">1</div> </div> Wed, 10 Nov 2021 17:31:33 +0000 ridingkm 2411 at https://www.vumc.org/global-health