Charles R. Horsburgh, Jr., M.D.
Timothy R. Sterling, M.D.
Predictors of Resistance Emergence Evaluation in MDR-TB Patients on Treatment (PREEMPT) (R01AI134430-01)
Multi-drug-resistant tuberculosis (MDR-TB) affects over 500,000 persons each year around the world and many patients die from it. During treatment, some patients discover that the germs with which they are infected have developed resistance to some of the antibiotics they are taking. The purpose of this study is to determine why this happens and to identify ways that this could be prevented.