Pancreatic islet cells distinct in mice and humans

Researchers in the lab of Roland Stein (Molecular Physiology & Biophysics), along with collaborators at UCSF, NC State, and UPenn, have shown distinct changes in human pancreatic islet cells throughout the course of life and the progression of type 2 diabetes. They also discovered distinct phenotypes in human islet cells compared to a mouse model.

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Post-transplant diabetes may be reversible

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Post-transplantation diabetes mellitus (PTDM), a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at Vanderbilt University Medical Center report.

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Dr. Maureen Gannon featured on News Channel 4 segment "4 Your Community"

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Genetic screen in worms reveals critical step in insulin synthesis

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Patrick Hu, MD, PhD, identified a previously unknown step in insulin synthesis, providing new clues to diabetes pathogenesis.

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Diabetes drug study explores cardiovascular risks for patients with kidney disease

Over the years there has been uncertainty over which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease. An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on this issue.

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Discovery may point to better treatments for Type 1 diabetes

Researchers at Vanderbilt University Medical Center led by an assistant professor of Pediatrics have made a paradigm-shifting discovery that could lead to new treatments, better health and longer life for patients with Type 1 diabetes.

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Study Drug Delays Type 1 Diabetes in High Risk Children and Adults

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A drug that targets the immune system can delay the onset of type 1 diabetes an average of two years in children and adults at high risk, according to findings from TrialNet’s Teplizumab (anti-CD3) Prevention Study published in the New England Journal of Medicine. Dr. Bill Russell is the PI of the TrialNet project. 

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Academic Pediatric Association honors Barkin

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Shari Barkin, MD, MSHS, division chief of General Pediatrics at Monroe Carell Jr. Children’s Hospital at Vanderbilt, was honored recently with the 2019 Academic Pediatric Association (APA) Research Award.

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Diabetes study reveals decline in pancreas volume for some

Investigators using MRI technology to study changes in pancreatic volume to better understand the progression of Type 1 diabetes include, from left, Melissa Hilmes, MD, Daniel Moore, MD, PhD, Alvin Powers, MD, Jon Williams, PhD, and Jack Virostko, PhD.

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) have discovered a progressive decline in pancreas volume over a one-year period in children and adolescents with newly diagnosed Type 1 diabetes.

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